Enzymatic bioorthogonal labeling, also known as the chemoenzymatic labeling strategy, provides an in vitro labeling method to detect structure-defined glycan epitopes. This method takes advantage of the substrate to tolerance of recombinant glycosyltransferase to label the target epitope with bioorthogonal groups carried by unnatural necleotide sugars.
However, the enzymatic bioorthogonal labeling strategy has not proven to be as popular as metabolic labeling for use in glycan analysis. The most important reason is the limited availability of unnatural nucleotide sugars which are functionalized with bioorthogonal reactive groups.
Our campany have the most advanced technology to produce unnatural nucleotide sugars modified with bioorthogonal groups. We are dedicated to provide products that will accelerate the further development and application of the enzymatic bioorthogonal labeling strategy for use in glycan analysis.
If you have any requirements not only the products listed on the website, Please send Email to sales@biochemsyn.com. Let's discuss if we could help you to get it!