Lactose-N-trisaccharide II - the star breast milk oligosaccharide that empowers infant health and precise nutrition

Lactose-N-trisaccharide II is one of the core oligosaccharide components in human breast milk and is known as the "essence of breast milk wisdom". It is not only a natural guardian of intestinal health in infants and young children, but also a key functional raw material at the forefront of research and development in the field of modern nutritional science and functional food.

Chemical Information

Chemical name: Lactose-N-trisaccharide II

Common name: LNT II

English name: Lacto-N-triose II

Chemical formula: C20H35NO16

Molecular weight: 545.49 g/mol

CAS number: 75645-27-1

Structural features

The unique structure of lactose-N-trisaccharide II is:

Core skeleton structure: As a trisaccharide, it is composed of glucose, galactose and N-acetylglucosamine linked by specific β-1,3 bonds. This structure is an indispensable key precursor for the synthesis of the entire milk-N-series oligosaccharide family (such as LNT, LNnT).

Biological recognition basis: The N-acetylglucosamine and galactose units at the end of its structure can be accurately recognized and utilized by the enzyme system secreted by specific probiotics (such as Bifidobacterium), thereby exerting its highly selective prebiotic effect.

Main applications and advantages

Core functional ingredients of high-end infant formula

Simulate breast milk function: Adding LNT II is a key strategy to make infant formula closer to breast milk in composition and function. It can accurately promote the proliferation of beneficial bacteria in the intestine (especially Bifidobacterium infantis) and help establish a healthy intestinal microecological environment dominated by beneficial bacteria.

Enhance the immune barrier: By promoting the growth of beneficial bacteria, LNT II helps inhibit the colonization of pathogenic bacteria, strengthens the intestinal physical and immune barrier functions, provides vital early immune protection for infants and young children, and reduces the risk of infection and allergies.

Innovative raw materials for next-generation functional foods and special medical foods

Precision prebiotics: Unlike traditional prebiotics (such as FOS/GOS) with a wide range of effects, LNT II has higher selectivity and can more accurately regulate specific beneficial bacteria, avoid uncomfortable reactions such as flatulence, and improve product tolerance.

"Gut-brain axis" and metabolic health: Cutting-edge research is exploring the potential benefits of HMOs such as LNT II on nervous system development through the "gut-brain axis", as well as their application prospects in regulating adult metabolic health and weight management.

Tools for basic research and biomedical development

Microbial interaction research: LNT II is an ideal tool molecule for studying the interaction between intestinal flora and the host, and can be used to reveal how HMOs specifically regulate the microbial ecosystem.

Glycobiology and drug development: As an important sugar chain structural unit, LNT II plays a key role in pathogen inhibition, cell recognition and signal transduction, and is a valuable basic raw material for the development of new anti-adhesion therapies or glycoconjugate drugs.

Conclusion

Lactose-N-trisaccharide II is not just a sugar molecule, it is a bridge between natural feeding and modern nutritional science. From creating a "gold standard" infant formula that is closer to breast milk, to developing precise nutrition solutions for the entire life cycle, its value is being continuously discovered.