3'-sialyllactose sodium salt-key oligosaccharide for early life nutrition CAS: 128596-80-5

3'-sialyllactose sodium salt is one of the most important and abundant sialylated components of human breast milk oligosaccharides. It is not only a natural guardian of infant growth and development, but also a star molecule with great potential in the development of modern nutritional science, prebiotic preparations and anti-infective drugs.

Chemical Information

· Chemical name: 3'-N-acetylneuraminic acid-lactose sodium salt

· Common name: 3'-sialyllactose sodium salt

· English name: 3'-N-Acetylneuramin-lactose Sodium Salt

· Chemical formula: C23H40NNaO19

· Molecular weight: 657.55 g/mol

· CAS number: 128596-80-5

Structural features

3'-sialyllactose sodium salt is composed of a sialic acid (N-acetylneuraminic acid) molecule connected to the galactosyl end of the lactose molecule through an α-2,3 glycosidic bond. Its unique features are:

· Precise molecular structure: Its α-2,3 linkage defines its interaction specificity with specific pathogens and cellular receptors, which is the structural basis of its biological function.

· Dual-functional module: It has both the nutritional unit of lactose and the functional unit of sialic acid, making it both a nutritional substrate and a key biorecognition signal molecule.

· Sodium salt form: Good water solubility and stability, convenient for storage, transportation and application in various formulas and preparations.

Main applications and advantages

1. Core functional ingredients of high-end infant formula

· Simulating breast milk function: Adding 3'-sialyllactose sodium salt is a key strategy to make infant formula milk powder closer to breast milk in composition and function, and can bridge some of the gaps in the immune and cognitive development of non-breastfed infants.

· Promote brain development: Sialic acid is an important component of brain gangliosides and glycoproteins and is crucial to the formation of early cognitive ability and memory in infants.

· Regulate intestinal health: As a natural prebiotic, it can selectively promote the proliferation of beneficial bacteria in the intestine (such as bifidobacteria), inhibit harmful bacteria, and help establish a healthy intestinal microecology.

2. Potential drug leads for anti-infection and immunomodulation

· Anti-adhesion effect: Many pathogenic bacteria (such as Helicobacter pylori, Streptococcus pneumoniae) and viruses adhere and infect by recognizing sialylated structures on the cell surface. 3'-Sialactose sodium salt can be used as a "molecular bait" to bind to pathogens and prevent them from attaching to host cells, thereby preventing and assisting in the treatment of infections.

· Modulates immune responses: It modulates immune cell responses and may show therapeutic potential in areas such as autoimmune diseases and inflammatory bowel disease.

3. Valuable tool for basic research and biotechnology development

· Glycobiology research: As a standard and key reagent with a clear structure, it is used to study sialic acid-mediated cell recognition, signal transduction and other life processes.

· Drug delivery system: Utilizing its targeting properties, it can be used to modify drug carriers (such as liposomes, nanoparticles) to achieve precise drug delivery to specific cells or tissues.

· Development of diagnostic reagents: Based on its high affinity to specific pathogen proteins, it can be used to develop new detection and diagnostic reagents.

Conclusion

3'-sialyllactose sodium salt is not just an oligosaccharide, it is a bridge connecting early health in life to future precision nutrition and disease prevention. From the innovation of the next generation of infant and young child nutrition, to the development of new anti-infective strategies, to the exploration of cutting-edge glycobiology, its value is constantly being discovered.